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MILLENNIUM MANAGEMENT LLC
> SYBX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | SYNLOGIC, INC. | SYBX | 19,020 | -76,414 | 8,179,000 | 8,106,000 | $430.02 |
| 12/31/2022 | SYNLOGIC, INC. | SYBX | 95,434 | 73,422 | 73,000 | 52,000 | $0.76 |
| 09/30/2022 | SYNLOGIC, INC. | SYBX | 22,012 | -103,114 | 21,000 | -123,000 | $0.95 |
| 06/30/2022 | SYNLOGIC, INC. | SYBX | 125,126 | 47,155 | 144,000 | -43,000 | $1.15 |
| 03/31/2022 | SYNLOGIC, INC. | SYBX | 77,971 | -215,888 | 187,000 | -524,000 | $2.40 |
| 12/31/2021 | SYNLOGIC, INC. | SYBX | 293,859 | 192,033 | 711,000 | 400,000 | $2.42 |
| 09/30/2021 | SYNLOGIC, INC. | SYBX | 101,826 | 24,371 | 311,000 | 10,000 | $3.05 |
| 06/30/2021 | SYNLOGIC, INC. | SYBX | 77,455 | 77,455 | 301,000 | 301,000 | $3.89 |
| 03/31/2021 | SYNLOGIC, INC. | SYBX | 0 | -58,294 | 0 | -126,000 | |
| 12/31/2020 | SYNLOGIC, INC. | SYBX | 58,294 | -253,504 | 126,000 | -507,000 | $2.16 |
| 06/30/2020 | SYNLOGIC, INC. | SYBX | 311,798 | 311,798 | 633,000 | 633,000 | $2.03 |
| 12/31/2018 | SYNLOGIC, INC. | SYBX | 0 | -65,848 | 0 | -936,000 | |
| 09/30/2018 | SYNLOGIC, INC. | SYBX | 65,848 | 41,257 | 936,000 | 694,000 | $14.21 |
| 06/30/2018 | SYNLOGIC, INC. | SYBX | 24,591 | 24,591 | 242,000 | 242,000 | $9.84 |
| 03/31/2018 | SYNLOGIC, INC. | SYBX | 0 | -48,085 | 0 | -466,000 | |
| 12/31/2017 | SYNLOGIC, INC. | SYBX | 48,085 | -60,788 | 466,000 | -1,604,000 | $9.69 |
| 09/30/2017 | SYNLOGIC, INC. | SYBX | 108,873 | 108,873 | 2,070,000 | 2,070,000 | $19.01 |
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