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FRED ALGER MANAGEMENT, LLC
> RGEN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | REPLIGEN CORP | RGEN | 570,131 | 77,835 | 80,650,731,000 | 80,558,617,000 | $141,460.00 |
| 09/30/2022 | REPLIGEN CORP | RGEN | 492,296 | -155,171 | 92,114,000 | -13,035,000 | $187.11 |
| 06/30/2022 | REPLIGEN CORP | RGEN | 647,467 | -378,391 | 105,149,000 | -87,805,000 | $162.40 |
| 03/31/2022 | REPLIGEN CORP | RGEN | 1,025,858 | -192,784 | 192,954,000 | -129,791,000 | $188.09 |
| 12/31/2021 | REPLIGEN CORP | RGEN | 1,218,642 | -355,356 | 322,745,000 | -132,125,000 | $264.84 |
| 09/30/2021 | REPLIGEN CORP | RGEN | 1,573,998 | 187,901 | 454,870,000 | 178,177,000 | $288.99 |
| 06/30/2021 | REPLIGEN CORP | RGEN | 1,386,097 | -91,081 | 276,693,000 | -10,485,000 | $199.62 |
| 03/31/2021 | REPLIGEN CORP | RGEN | 1,477,178 | 166,364 | 287,178,000 | 35,987,000 | $194.41 |
| 12/31/2020 | REPLIGEN CORP | RGEN | 1,310,814 | 166,836 | 251,191,000 | 82,408,000 | $191.63 |
| 09/30/2020 | REPLIGEN CORP | RGEN | 1,143,978 | 130,530 | 168,783,000 | 43,511,000 | $147.54 |
| 06/30/2020 | REPLIGEN CORP | RGEN | 1,013,448 | -22,499 | 125,272,000 | 25,262,000 | $123.61 |
| 03/31/2020 | REPLIGEN CORP | RGEN | 1,035,947 | -197,009 | 100,010,000 | -14,038,000 | $96.54 |
| 12/31/2019 | REPLIGEN CORP | RGEN | 1,232,956 | -143,450 | 114,048,000 | 8,491,000 | $92.50 |
| 09/30/2019 | REPLIGEN CORP | RGEN | 1,376,406 | -473,032 | 105,557,000 | -53,402,000 | $76.69 |
| 06/30/2019 | REPLIGEN CORP | RGEN | 1,849,438 | 206,393 | 158,959,000 | 61,888,000 | $85.95 |
| 03/31/2019 | REPLIGEN CORP | RGEN | 1,643,045 | 548,054 | 97,071,000 | 39,321,000 | $59.08 |
| 12/31/2018 | REPLIGEN CORP | RGEN | 1,094,991 | 35,503 | 57,750,000 | -1,009,000 | $52.74 |
| 09/30/2018 | REPLIGEN CORP | RGEN | 1,059,488 | 318,914 | 58,759,000 | 23,922,000 | $55.46 |
| 06/30/2018 | REPLIGEN CORP | RGEN | 740,574 | 363,339 | 34,837,000 | 21,189,000 | $47.04 |
| 03/31/2018 | REPLIGEN CORP | RGEN | 377,235 | 377,235 | 13,648,000 | 13,648,000 | $36.18 |
| 12/31/2017 | REPLIGEN CORP | RGEN | 0 | -36,000 | 0 | -1,380,000 | |
| 09/30/2017 | REPLIGEN CORP | RGEN | 36,000 | -2,200 | 1,380,000 | -203,000 | $38.33 |
| 06/30/2017 | REPLIGEN CORP | RGEN | 38,200 | 38,200 | 1,583,000 | 1,583,000 | $41.44 |
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