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WELLINGTON MANAGEMENT GROUP LLP
> BPMC
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Blueprint Medicines Corp | BPMC | 4,923,714 | -213,989 | 311,178,725,000 | 80,033,468,000 | $63,200.00 |
| 03/31/2023 | Blueprint Medicines Corp | BPMC | 5,137,703 | 1,313,724 | 231,145,257,000 | 230,893,295,000 | $44,990.00 |
| 09/30/2022 | Blueprint Medicines Corp | BPMC | 3,823,979 | 1,324,305 | 251,962,000 | 125,705,000 | $65.89 |
| 06/30/2022 | Blueprint Medicines Corp | BPMC | 2,499,674 | -1,409,270 | 126,257,000 | -123,446,000 | $50.51 |
| 03/31/2022 | Blueprint Medicines Corp | BPMC | 3,908,944 | 431,619 | 249,703,000 | -122,754,000 | $63.88 |
| 12/31/2021 | Blueprint Medicines Corp | BPMC | 3,477,325 | 278,284 | 372,457,000 | 43,564,000 | $107.11 |
| 09/30/2021 | Blueprint Medicines Corp | BPMC | 3,199,041 | 1,182,979 | 328,893,000 | 151,560,000 | $102.81 |
| 06/30/2021 | Blueprint Medicines Corp | BPMC | 2,016,062 | 680,785 | 177,333,000 | 47,504,000 | $87.96 |
| 03/31/2021 | Blueprint Medicines Corp | BPMC | 1,335,277 | 298,647 | 129,829,000 | 13,570,000 | $97.23 |
| 12/31/2020 | Blueprint Medicines Corp | BPMC | 1,036,630 | 64,963 | 116,259,000 | 26,185,000 | $112.15 |
| 09/30/2020 | Blueprint Medicines Corp | BPMC | 971,667 | -376,236 | 90,074,000 | -15,062,000 | $92.70 |
| 06/30/2020 | Blueprint Medicines Corp | BPMC | 1,347,903 | -152,559 | 105,136,000 | 17,388,000 | $78.00 |
| 03/31/2020 | Blueprint Medicines Corp | BPMC | 1,500,462 | -966,865 | 87,748,000 | -109,911,000 | $58.48 |
| 12/31/2019 | Blueprint Medicines Corp | BPMC | 2,467,327 | -30,718 | 197,659,000 | 14,127,000 | $80.11 |
| 09/30/2019 | Blueprint Medicines Corp | BPMC | 2,498,045 | -244,196 | 183,532,000 | -75,143,000 | $73.47 |
| 06/30/2019 | Blueprint Medicines Corp | BPMC | 2,742,241 | 204,802 | 258,675,000 | 55,553,000 | $94.33 |
| 03/31/2019 | Blueprint Medicines Corp | BPMC | 2,537,439 | -94,420 | 203,122,000 | 61,239,000 | $80.05 |
| 12/31/2018 | Blueprint Medicines Corp | BPMC | 2,631,859 | -309,658 | 141,883,000 | -87,732,000 | $53.91 |
| 09/30/2018 | Blueprint Medicines Corp | BPMC | 2,941,517 | 241,118 | 229,615,000 | 58,193,000 | $78.06 |
| 06/30/2018 | Blueprint Medicines Corp | BPMC | 2,700,399 | 24,249 | 171,422,000 | -73,981,000 | $63.48 |
| 03/31/2018 | Blueprint Medicines Corp | BPMC | 2,676,150 | 207,775 | 245,403,000 | 59,263,000 | $91.70 |
| 12/31/2017 | Blueprint Medicines Corp | BPMC | 2,468,375 | -738,397 | 186,140,000 | -37,275,000 | $75.41 |
| 12/29/2017 | Blueprint Medicines Corp | BPMC | 2,468,375 | -738,397 | 186,140,159 | -37,274,841 | $75.41 |
| 09/30/2017 | Blueprint Medicines Corp | BPMC | 3,206,772 | 97,075 | 223,415,000 | 65,848,000 | $69.67 |
| 06/30/2017 | Blueprint Medicines Corp | BPMC | 3,109,697 | -711,887 | 157,567,000 | 4,741,000 | $50.67 |
| 03/31/2017 | Blueprint Medicines Corp | BPMC | 3,821,584 | 2,549,623 | 152,826,000 | 117,148,000 | $39.99 |
| 12/31/2016 | Blueprint Medicines Corp | BPMC | 1,271,961 | 149,745 | 35,678,000 | 2,349,000 | $28.05 |
| 09/30/2016 | Blueprint Medicines Corp | BPMC | 1,122,216 | 1,122,216 | 33,329,000 | 33,329,000 | $29.70 |
| 06/30/2016 | Blueprint Medicines Corp | BPMC | 1,149,078 | 1,149,078 | 23,270,000 | 23,270,000 | $20.25 |
| 03/31/2016 | Blueprint Medicines Corp | BPMC | 536,416 | 63,415 | 9,682,000 | -2,777,000 | $18.05 |
| 12/31/2015 | Blueprint Medicines Corp | BPMC | 473,001 | -792,172 | 12,459,000 | -14,540,000 | $26.34 |
| 09/30/2015 | Blueprint Medicines Corp | BPMC | 1,265,173 | 124,295 | 26,999,000 | -3,035,000 | $21.34 |
| 06/30/2015 | Blueprint Medicines Corp | BPMC | 1,140,878 | 1,140,878 | 30,034,000 | 30,034,000 | $26.33 |
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