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WADDELL & REED FINANCIAL INC
> VRTX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 03/31/2021 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,396,827 | 10 | 300,164,000 | -29,960,000 | $214.89 |
| 12/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,396,817 | -343,440 | 330,124,000 | -143,435,000 | $236.34 |
| 09/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,740,257 | -18,171 | 473,559,000 | -36,930,000 | $272.12 |
| 06/30/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 1,758,428 | -304,949 | 510,489,000 | 19,508,000 | $290.31 |
| 03/31/2020 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,063,377 | -243,878 | 490,981,000 | -14,192,000 | $237.95 |
| 12/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,307,255 | 67,781 | 505,173,000 | 125,761,000 | $218.95 |
| 09/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,239,474 | 4,829 | 379,412,000 | -30,377,000 | $169.42 |
| 06/30/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,234,645 | 133,930 | 409,789,000 | 23,362,000 | $183.38 |
| 03/31/2019 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,100,715 | -70,342 | 386,427,000 | 26,661,000 | $183.95 |
| 12/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,171,057 | -37,421 | 359,766,000 | -65,896,000 | $165.71 |
| 09/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,208,478 | -19,877 | 425,662,000 | 46,931,000 | $192.74 |
| 06/30/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,228,355 | -132,591 | 378,731,000 | -6,056,000 | $169.96 |
| 03/31/2018 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,360,946 | -497,901 | 384,787,000 | -43,640,000 | $162.98 |
| 12/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,858,847 | -741,394 | 428,427,000 | -118,954,000 | $149.86 |
| 09/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,600,241 | -426,182 | 547,381,000 | 28,495,000 | $152.04 |
| 06/30/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,026,423 | 392,420 | 518,886,000 | 121,507,000 | $128.87 |
| 03/31/2017 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,634,003 | -214,602 | 397,379,000 | 113,852,000 | $109.35 |
| 12/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,848,605 | -193,243 | 283,527,000 | -68,962,000 | $73.67 |
| 09/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,041,848 | 432,848 | 352,489,000 | 97,260,000 | $87.21 |
| 06/30/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,258,478 | -303,165 | 366,315,000 | 3,710,000 | $86.02 |
| 03/31/2016 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,561,643 | 952,643 | 362,605,000 | 107,376,000 | $79.49 |
| 12/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,987,763 | 1,378,763 | 627,610,000 | 372,381,000 | $125.83 |
| 09/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,950,890 | 1,341,890 | 515,586,000 | 260,357,000 | $104.14 |
| 06/30/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,735,874 | 1,126,874 | 584,785,000 | 329,556,000 | $123.48 |
| 03/31/2015 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 4,217,388 | 608,388 | 497,525,000 | 242,296,000 | $117.97 |
| 12/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,832,300 | 223,300 | 455,278,000 | 200,049,000 | $118.80 |
| 09/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,837,000 | 228,000 | 430,933,000 | 175,704,000 | $112.31 |
| 06/30/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 0 | -3,609,000 | 0 | -255,229,000 | |
| 03/31/2014 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,609,000 | 3,609,000 | 255,229,000 | 255,229,000 | $70.72 |
| 12/31/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,565,700 | 3,565,700 | 264,931,000 | 264,931,000 | $74.30 |
| 09/30/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 3,178,600 | 3,178,600 | 241,001,000 | 241,001,000 | $75.82 |
| 06/30/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,911,100 | 280,300 | 232,509,000 | 87,868,000 | $79.87 |
| 03/31/2013 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,630,800 | 145,200 | 144,641,000 | 40,394,000 | $54.98 |
| 12/31/2012 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,485,600 | 16,700 | 104,247,000 | -33,888,000 | $41.94 |
| 09/30/2012 | VERTEX PHARMACEUTICALS INC / MA | VRTX | 2,468,900 | 20,900 | 138,135,000 | 1,243,000 | $55.95 |
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