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ESSEX INVESTMENT MANAGEMENT CO LLC
> SAGE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Sage Therapeutics, Inc. | SAGE | 20,360 | 20,360 | 957,327,000 | 957,327,000 | $47,019.99 |
| 09/30/2019 | Sage Therapeutics, Inc. | SAGE | 0 | -6,332 | 0 | -1,159,000 | |
| 06/30/2019 | Sage Therapeutics, Inc. | SAGE | 6,332 | 6,332 | 1,159,000 | 1,159,000 | $183.04 |
| 03/31/2019 | Sage Therapeutics, Inc. | SAGE | 0 | -9,961 | 0 | -954,000 | |
| 12/31/2018 | Sage Therapeutics, Inc. | SAGE | 9,961 | 6,319 | 954,000 | 440,000 | $95.77 |
| 09/30/2018 | Sage Therapeutics, Inc. | SAGE | 3,642 | -1,460 | 514,000 | -285,000 | $141.13 |
| 06/30/2018 | Sage Therapeutics, Inc. | SAGE | 5,102 | 173 | 799,000 | 5,000 | $156.61 |
| 03/31/2018 | Sage Therapeutics, Inc. | SAGE | 4,929 | -1,502 | 794,000 | -265,000 | $161.09 |
| 12/31/2017 | Sage Therapeutics, Inc. | SAGE | 6,431 | -395 | 1,059,000 | 634,000 | $164.67 |
| 09/30/2017 | Sage Therapeutics, Inc. | SAGE | 6,826 | -24,834 | 425,000 | -2,096,000 | $62.26 |
| 06/30/2017 | Sage Therapeutics, Inc. | SAGE | 31,660 | 787 | 2,521,000 | 327,000 | $79.63 |
| 03/31/2017 | Sage Therapeutics, Inc. | SAGE | 30,873 | 19,204 | 2,194,000 | 1,598,000 | $71.07 |
| 12/31/2016 | Sage Therapeutics, Inc. | SAGE | 11,669 | 11,669 | 596,000 | 596,000 | $51.08 |
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