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CITADEL ADVISORS LLC
> SAGE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Sage Therapeutics, Inc. | SAGE | 223,826 | 183,761 | 10,524,299,000 | 8,996,220,000 | $47,020.00 |
| 12/31/2022 | Sage Therapeutics, Inc. | SAGE | 40,065 | -123,031 | 1,528,079,000 | 1,521,692,000 | $38,140.00 |
| 09/30/2022 | Sage Therapeutics, Inc. | SAGE | 163,096 | 116,406 | 6,387,000 | 4,879,000 | $39.16 |
| 06/30/2022 | Sage Therapeutics, Inc. | SAGE | 46,690 | -59,256 | 1,508,000 | -1,999,000 | $32.30 |
| 03/31/2022 | Sage Therapeutics, Inc. | SAGE | 105,946 | -991,899 | 3,507,000 | -43,195,000 | $33.10 |
| 12/31/2021 | Sage Therapeutics, Inc. | SAGE | 1,097,845 | 427,855 | 46,702,000 | 17,014,000 | $42.54 |
| 09/30/2021 | Sage Therapeutics, Inc. | SAGE | 669,990 | 24,180 | 29,688,000 | -7,001,000 | $44.31 |
| 06/30/2021 | Sage Therapeutics, Inc. | SAGE | 645,810 | 614,791 | 36,689,000 | 34,367,000 | $56.81 |
| 03/31/2021 | Sage Therapeutics, Inc. | SAGE | 31,019 | -468,425 | 2,322,000 | -40,885,000 | $74.86 |
| 12/31/2020 | Sage Therapeutics, Inc. | SAGE | 499,444 | -925,619 | 43,207,000 | -43,893,000 | $86.51 |
| 09/30/2020 | Sage Therapeutics, Inc. | SAGE | 1,425,063 | -338,550 | 87,100,000 | 13,769,000 | $61.12 |
| 06/30/2020 | Sage Therapeutics, Inc. | SAGE | 1,763,613 | 1,155,806 | 73,331,000 | 55,875,000 | $41.58 |
| 03/31/2020 | Sage Therapeutics, Inc. | SAGE | 607,807 | 175,585 | 17,456,000 | -13,747,000 | $28.72 |
| 12/31/2019 | Sage Therapeutics, Inc. | SAGE | 432,222 | 341,925 | 31,203,000 | 18,535,000 | $72.19 |
| 09/30/2019 | Sage Therapeutics, Inc. | SAGE | 90,297 | 84,374 | 12,668,000 | 11,584,000 | $140.29 |
| 06/30/2019 | Sage Therapeutics, Inc. | SAGE | 5,923 | -24,964 | 1,084,000 | -3,829,000 | $183.02 |
| 03/31/2019 | Sage Therapeutics, Inc. | SAGE | 30,887 | 570 | 4,913,000 | 2,009,000 | $159.06 |
| 12/31/2018 | Sage Therapeutics, Inc. | SAGE | 30,317 | -148,705 | 2,904,000 | -22,383,000 | $95.79 |
| 09/30/2018 | Sage Therapeutics, Inc. | SAGE | 179,022 | 153,861 | 25,287,000 | 21,348,000 | $141.25 |
| 06/30/2018 | Sage Therapeutics, Inc. | SAGE | 25,161 | -51,785 | 3,939,000 | -8,454,000 | $156.55 |
| 03/31/2018 | Sage Therapeutics, Inc. | SAGE | 76,946 | 39,995 | 12,393,000 | 6,307,000 | $161.06 |
| 12/31/2017 | Sage Therapeutics, Inc. | SAGE | 36,951 | -71,249 | 6,086,000 | -655,000 | $164.70 |
| 09/30/2017 | Sage Therapeutics, Inc. | SAGE | 108,200 | 93,289 | 6,741,000 | 5,553,000 | $62.30 |
| 06/30/2017 | Sage Therapeutics, Inc. | SAGE | 14,911 | -90,621 | 1,188,000 | -6,312,000 | $79.67 |
| 03/31/2017 | Sage Therapeutics, Inc. | SAGE | 105,532 | 30,527 | 7,500,000 | 3,670,000 | $71.07 |
| 12/31/2016 | Sage Therapeutics, Inc. | SAGE | 75,005 | -1,199,408 | 3,830,000 | -54,857,000 | $51.06 |
| 09/30/2016 | Sage Therapeutics, Inc. | SAGE | 1,274,413 | 1,274,413 | 58,687,000 | 58,687,000 | $46.05 |
| 06/30/2016 | Sage Therapeutics, Inc. | SAGE | 650,008 | 164,497 | 19,585,000 | 4,020,000 | $30.13 |
| 03/31/2016 | Sage Therapeutics, Inc. | SAGE | 485,511 | 245,838 | 15,565,000 | 1,592,000 | $32.06 |
| 12/31/2015 | Sage Therapeutics, Inc. | SAGE | 239,673 | 239,673 | 13,973,000 | 13,973,000 | $58.30 |
| 09/30/2015 | Sage Therapeutics, Inc. | SAGE | 0 | -13,054 | 0 | -656,000 | |
| 06/30/2015 | Sage Therapeutics, Inc. | SAGE | 0 | -13,054 | 0 | -656,000 | |
| 03/31/2015 | Sage Therapeutics, Inc. | SAGE | 13,054 | -41,408 | 656,000 | -1,337,000 | $50.25 |
| 12/31/2014 | Sage Therapeutics, Inc. | SAGE | 54,462 | 13,425 | 1,993,000 | 700,000 | $36.59 |
| 09/30/2014 | Sage Therapeutics, Inc. | SAGE | 41,037 | 41,037 | 1,293,000 | 1,293,000 | $31.51 |
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