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BAKER BROS. ADVISORS LP
> PRLD
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 45,557,208,000 | -15,590,689,000 | $4,500.00 |
| 12/31/2022 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 61,147,897,000 | 61,080,979,000 | $6,040.00 |
| 09/30/2022 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 66,918,000 | 14,072,000 | $6.61 |
| 06/30/2022 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 52,846,000 | -17,008,000 | $5.22 |
| 03/31/2022 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 69,854,000 | -56,188,000 | $6.90 |
| 12/31/2021 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 126,042,000 | -190,328,000 | $12.45 |
| 09/30/2021 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 316,370,000 | 26,525,000 | $31.25 |
| 06/30/2021 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 0 | 289,845,000 | -148,820,000 | $28.63 |
| 03/31/2021 | Prelude Therapeutics Inc | PRLD | 10,123,824 | 5,188 | 438,665,000 | -285,323,000 | $43.33 |
| 12/31/2020 | Prelude Therapeutics Inc | PRLD | 10,118,636 | 0 | 723,988,000 | 419,113,000 | $71.55 |
| 09/30/2020 | Prelude Therapeutics Inc | PRLD | 10,118,636 | 10,118,636 | 304,875,000 | 304,875,000 | $30.13 |
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