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BAKER BROS. ADVISORS LP
> PRAX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Praxis Precision Medicines, Inc. | PRAX | 1,879,915 | 49,600 | 2,161,902,000 | -2,194,248,000 | $1,150.00 |
| 12/31/2022 | Praxis Precision Medicines, Inc. | PRAX | 1,830,315 | 1,830,315 | 4,356,150,000 | 4,356,150,000 | $2,380.00 |
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