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JANUS HENDERSON GROUP PLC
> INSM
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | INSMED Inc | INSM | 2,195,188 | -801,064 | 46,317,842,000 | -13,545,162,000 | $21,099.72 |
| 12/31/2022 | INSMED Inc | INSM | 2,996,252 | -425,074 | 59,863,004,000 | 59,789,307,000 | $19,979.30 |
| 09/30/2022 | INSMED Inc | INSM | 3,421,326 | -3,579,011 | 73,697,000 | -64,354,000 | $21.54 |
| 06/30/2022 | INSMED Inc | INSM | 7,000,337 | -677,929 | 138,051,000 | -42,391,000 | $19.72 |
| 03/31/2022 | INSMED Inc | INSM | 7,678,266 | -203,292 | 180,442,000 | -34,258,000 | $23.50 |
| 12/31/2021 | INSMED Inc | INSM | 7,881,558 | -106,341 | 214,700,000 | -5,285,000 | $27.24 |
| 09/30/2021 | INSMED Inc | INSM | 7,987,899 | 35,898 | 219,985,000 | -6,332,000 | $27.54 |
| 06/30/2021 | INSMED Inc | INSM | 7,952,001 | 1,733,425 | 226,317,000 | 14,509,000 | $28.46 |
| 03/31/2021 | INSMED Inc | INSM | 6,218,576 | 396,163 | 211,808,000 | 17,977,000 | $34.06 |
| 12/31/2020 | INSMED Inc | INSM | 5,822,413 | -346,754 | 193,831,000 | -4,447,000 | $33.29 |
| 09/30/2020 | INSMED Inc | INSM | 6,169,167 | -3,073,205 | 198,278,000 | -56,256,000 | $32.14 |
| 06/30/2020 | INSMED Inc | INSM | 9,242,372 | 411,016 | 254,534,000 | 112,968,000 | $27.54 |
| 03/31/2020 | INSMED Inc | INSM | 8,831,356 | -2,835,922 | 141,566,000 | -137,048,000 | $16.03 |
| 12/31/2019 | INSMED Inc | INSM | 11,667,278 | -453,301 | 278,614,000 | 64,807,000 | $23.88 |
| 09/30/2019 | INSMED Inc | INSM | 12,120,579 | 12,120,579 | 213,807,000 | 213,807,000 | $17.64 |
| 06/30/2019 | INSMED Inc | INSM | 0 | -11,302,434 | 0 | -328,562,000 | |
| 03/31/2019 | INSMED Inc | INSM | 11,302,434 | -119,027 | 328,562,000 | 178,712,000 | $29.07 |
| 12/31/2018 | INSMED Inc | INSM | 11,421,461 | 2,116,129 | 149,850,000 | -38,304,000 | $13.12 |
| 09/30/2018 | INSMED Inc | INSM | 9,305,332 | 1,850,394 | 188,154,000 | 11,845,000 | $20.22 |
| 08/10/2018 | INSMED Inc | INSM | 8,197,060 | 1,950,718 | 182,138,673 | 41,470,673 | $22.22 |
| 06/30/2018 | INSMED Inc | INSM | 7,454,938 | 1,208,596 | 176,309,000 | 35,641,000 | $23.65 |
| 03/31/2018 | INSMED Inc | INSM | 6,246,342 | 283,136 | 140,668,000 | -45,265,000 | $22.52 |
| 12/31/2017 | INSMED Inc | INSM | 5,963,206 | 2,002,458 | 185,933,000 | 62,318,000 | $31.18 |
| 09/30/2017 | INSMED Inc | INSM | 3,960,748 | 2,312,045 | 123,615,000 | 123,586,708 | $31.21 |
| 06/30/2017 | INSMED Inc | INSM | 1,648,703 | 1,648,703 | 28,292 | 28,292 | $0.02 |
| 06/30/2015 | INSMED Inc | INSM | 0 | -75,000 | 0 | -1,560,000 | |
| 03/31/2015 | INSMED Inc | INSM | 75,000 | 75,000 | 1,560,000 | 1,560,000 | $20.80 |
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