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NEEDHAM INVESTMENT MANAGEMENT LLC
> TMO
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 34,000 | 0 | 18,723,460,000 | 18,706,215,000 | $550,690.00 |
| 09/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 34,000 | -500 | 17,245,000 | -1,498,000 | $507.21 |
| 06/30/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 34,500 | -3,500 | 18,743,000 | -3,702,000 | $543.28 |
| 03/31/2022 | THERMO FISHER SCIENTIFIC INC. | TMO | 38,000 | 0 | 22,445,000 | -2,910,000 | $590.66 |
| 12/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 38,000 | -3,500 | 25,355,000 | 4,420,000 | $667.24 |
| 06/30/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 41,500 | 0 | 20,935,000 | 1,995,000 | $504.46 |
| 03/31/2021 | THERMO FISHER SCIENTIFIC INC. | TMO | 41,500 | 0 | 18,940,000 | -390,000 | $456.39 |
| 12/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 41,500 | -1,750 | 19,330,000 | 235,000 | $465.78 |
| 09/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 43,250 | -3,750 | 19,095,000 | 2,065,000 | $441.50 |
| 06/30/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 47,000 | -8,000 | 17,030,000 | 1,432,000 | $362.34 |
| 03/31/2020 | THERMO FISHER SCIENTIFIC INC. | TMO | 55,000 | 0 | 15,598,000 | -2,270,000 | $283.60 |
| 12/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 55,000 | 0 | 17,868,000 | 1,848,000 | $324.87 |
| 09/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 55,000 | 0 | 16,020,000 | -132,000 | $291.27 |
| 06/30/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 55,000 | -6,500 | 16,152,000 | -682,000 | $293.67 |
| 03/31/2019 | THERMO FISHER SCIENTIFIC INC. | TMO | 61,500 | -6,350 | 16,834,000 | 1,649,000 | $273.72 |
| 12/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 67,850 | -6,650 | 15,185,000 | -2,999,000 | $223.80 |
| 09/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 74,500 | -10,000 | 18,184,000 | 681,000 | $244.08 |
| 06/30/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 84,500 | -500 | 17,503,000 | -47,000 | $207.14 |
| 03/31/2018 | THERMO FISHER SCIENTIFIC INC. | TMO | 85,000 | -2,500 | 17,550,000 | 935,000 | $206.47 |
| 12/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 87,500 | -5,000 | 16,615,000 | -886,000 | $189.89 |
| 09/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 92,500 | -2,000 | 17,501,000 | 1,014,000 | $189.20 |
| 06/30/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 94,500 | -13,500 | 16,487,000 | -102,000 | $174.47 |
| 03/31/2017 | THERMO FISHER SCIENTIFIC INC. | TMO | 108,000 | -32,500 | 16,589,000 | -3,235,000 | $153.60 |
| 12/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 140,500 | -5,000 | 19,824,000 | -3,319,000 | $141.10 |
| 09/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 145,500 | -5,000 | 23,143,000 | 905,000 | $159.06 |
| 06/30/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 150,500 | -63,500 | 22,238,000 | 4,127,000 | $147.76 |
| 03/31/2016 | THERMO FISHER SCIENTIFIC INC. | TMO | 165,000 | -49,000 | 23,362,000 | 5,251,000 | $141.59 |
| 12/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 165,000 | -49,000 | 23,406,000 | 5,295,000 | $141.85 |
| 09/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 165,000 | -49,000 | 20,176,000 | 2,065,000 | $122.28 |
| 06/30/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 165,000 | -49,000 | 21,410,000 | 3,299,000 | $129.76 |
| 03/31/2015 | THERMO FISHER SCIENTIFIC INC. | TMO | 165,000 | -49,000 | 22,167,000 | 4,056,000 | $134.35 |
| 12/31/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 167,500 | -46,500 | 20,986,000 | 2,875,000 | $125.29 |
| 09/30/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 165,000 | -49,000 | 20,081,000 | 1,970,000 | $121.70 |
| 06/30/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 200,000 | -14,000 | 23,600,000 | 5,489,000 | $118.00 |
| 03/31/2014 | THERMO FISHER SCIENTIFIC INC. | TMO | 214,000 | 0 | 25,731,000 | 7,620,000 | $120.24 |
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