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Palo Alto Investors LP
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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AMICUS THERAPEUTICS, INC. | FOLD | 10,524,022 | 0 | 132,181,716,000 | 15,470,312,000 | $12,560.00 |
| 03/31/2023 | AMICUS THERAPEUTICS, INC. | FOLD | 10,524,022 | 30,300 | 116,711,404,000 | -11,416,942,000 | $11,090.00 |
| 12/31/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 10,493,722 | 645,948 | 128,128,346,000 | 128,025,535,000 | $12,210.00 |
| 09/30/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 9,847,774 | 0 | 102,811,000 | -2,954,000 | $10.44 |
| 06/30/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 9,847,774 | -55,987 | 105,765,000 | 11,976,000 | $10.74 |
| 03/31/2022 | AMICUS THERAPEUTICS, INC. | FOLD | 9,903,761 | -210,282 | 93,789,000 | -23,028,000 | $9.47 |
| 12/31/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 10,114,043 | 0 | 116,817,000 | 20,228,000 | $11.55 |
| 09/30/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 10,114,043 | 111,600 | 96,589,000 | 165,000 | $9.55 |
| 06/30/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 10,002,443 | 241,400 | 96,424,000 | -15,000 | $9.64 |
| 03/31/2021 | AMICUS THERAPEUTICS, INC. | FOLD | 9,761,043 | 1,893,929 | 96,439,000 | -85,213,000 | $9.88 |
| 12/31/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 7,867,114 | 0 | 181,652,000 | 70,568,000 | $23.09 |
| 09/30/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 7,867,114 | 532,400 | 111,084,000 | 477,000 | $14.12 |
| 06/30/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 7,334,714 | -112,904 | 110,607,000 | 41,791,000 | $15.08 |
| 03/31/2020 | AMICUS THERAPEUTICS, INC. | FOLD | 7,447,618 | 33,698 | 68,816,000 | -3,396,000 | $9.24 |
| 12/31/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 7,413,920 | 251,000 | 72,212,000 | 14,765,000 | $9.74 |
| 09/30/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 7,162,920 | -633,379 | 57,447,000 | -39,851,000 | $8.02 |
| 06/30/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 7,796,299 | 176,466 | 97,298,000 | -6,332,000 | $12.48 |
| 03/31/2019 | AMICUS THERAPEUTICS, INC. | FOLD | 7,619,833 | 218,512 | 103,630,000 | 32,725,000 | $13.60 |
| 12/31/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 7,401,321 | 1,035,174 | 70,905,000 | -6,062,000 | $9.58 |
| 09/30/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 6,366,147 | 197,800 | 76,967,000 | -19,383,000 | $12.09 |
| 06/30/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 6,168,347 | 20,518 | 96,350,000 | 3,887,000 | $15.62 |
| 03/31/2018 | AMICUS THERAPEUTICS, INC. | FOLD | 6,147,829 | 141,807 | 92,463,000 | 6,036,000 | $15.04 |
| 12/31/2017 | AMICUS THERAPEUTICS, INC. | FOLD | 6,006,022 | -1,414,266 | 86,427,000 | -25,471,000 | $14.39 |
| 09/30/2017 | AMICUS THERAPEUTICS, INC. | FOLD | 7,420,288 | -520,500 | 111,898,000 | 31,934,000 | $15.08 |
| 06/30/2017 | AMICUS THERAPEUTICS, INC. | FOLD | 7,940,788 | 57,800 | 79,964,000 | 23,758,000 | $10.07 |
| 03/31/2017 | AMICUS THERAPEUTICS, INC. | FOLD | 7,882,988 | 1,472,958 | 56,206,000 | 24,348,000 | $7.13 |
| 12/31/2016 | AMICUS THERAPEUTICS, INC. | FOLD | 6,410,030 | 724,642 | 31,858,000 | -10,214,000 | $4.97 |
| 09/30/2016 | AMICUS THERAPEUTICS, INC. | FOLD | 5,685,388 | 1,676,013 | 42,072,000 | 20,181,000 | $7.40 |
| 06/30/2016 | AMICUS THERAPEUTICS, INC. | FOLD | 4,009,375 | 4,009,375 | 21,891,000 | 21,891,000 | $5.46 |
| 03/31/2016 | AMICUS THERAPEUTICS, INC. | FOLD | 3,551,173 | 0 | 30,007,000 | -4,439,000 | $8.45 |
| 12/31/2015 | AMICUS THERAPEUTICS, INC. | FOLD | 3,551,173 | -1,229,497 | 34,446,000 | 21,634,000 | $9.70 |
| 09/30/2015 | AMICUS THERAPEUTICS, INC. | FOLD | 1,974,376 | -2,806,294 | 27,622,000 | 14,810,000 | $13.99 |
| 06/30/2015 | AMICUS THERAPEUTICS, INC. | FOLD | 1,974,376 | -2,806,294 | 27,937,000 | 15,125,000 | $14.15 |
| 03/31/2015 | AMICUS THERAPEUTICS, INC. | FOLD | 1,956,376 | -2,824,294 | 21,285,000 | 8,473,000 | $10.88 |
| 12/31/2014 | AMICUS THERAPEUTICS, INC. | FOLD | 1,956,376 | -2,824,294 | 16,277,000 | 3,465,000 | $8.32 |
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