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ORBIMED CAPITAL LLC
> ADLR
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 09/30/2017 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2017 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2016 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2016 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2016 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2012 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2012 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2012 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2011 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2011 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2011 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2011 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2010 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2010 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2010 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2010 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2009 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2009 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2009 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2009 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2008 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2008 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2008 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2008 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2007 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2007 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2007 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2007 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2006 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 09/30/2006 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 06/30/2006 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2006 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 12/31/2005 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 08/16/2004 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
| 03/31/2004 | ADOLOR CORP | ADLR | 0 | -315,000 | 0 | -4,381,650 | |
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