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ACELYRIN, Inc.

Portfolio as of:
NameSharesChangeValue% Port% OSHistDate
AyurMaya Capital Management Company, LP 9,334,7359,334,735195,095,962,000100.00  Hist 06/30/2023
FMR LLC 7,456,2387,456,238150,793,350,0000.01  Hist 06/30/2023
CITADEL ADVISORS LLC 6,039,6576,039,657121,333,453,0000.03  Hist 06/30/2023
ORBIMED ADVISORS LLC 5,326,3025,326,302111,319,712,0002.02  Hist 06/30/2023
Opaleye Management Inc. 4,158,6384,158,63886,915,534,00020.79  Hist 06/30/2023
venBio Partners LLC 3,857,2303,857,23080,616,107,00029.18  Hist 06/30/2023
JPMORGAN CHASE & CO 3,703,3383,703,33877,399,765,0000.01  Hist 06/30/2023
VANGUARD GROUP INC 3,072,1803,072,18064,208,562,0000.00  Hist 06/30/2023
Ikarian Capital, LLC 2,918,4262,918,42660,995,103,0009.71  Hist 06/30/2023
CHI Advisors LLC 2,663,8062,663,80655,673,548,00016.89  Hist 06/30/2023
Samsara BioCapital, LLC 2,256,0222,256,02247,150,860,0008.28  Hist 06/30/2023
TYBOURNE CAPITAL MANAGEMENT (HK) LTD 2,230,4422,230,44246,616,238,0005.04  Hist 06/30/2023
DRIEHAUS CAPITAL MANAGEMENT LLC 1,758,7971,758,79736,758,857,0000.46  Hist 06/30/2023
Decheng Capital Management III (Cayman), LLC 1,554,4171,554,41732,487,315,00010.19  Hist 06/30/2023
GENERAL ATLANTIC, L.P. 1,500,0001,500,00031,350,000,0000.49  Hist 06/30/2023
MARSHALL WACE, LLP 1,161,5281,161,52824,275,935,0000.05  Hist 06/30/2023
ALLIANCEBERNSTEIN L.P. 1,143,2741,143,27423,894,427,0000.01  Hist 06/30/2023
WELLINGTON MANAGEMENT GROUP LLP 1,048,2791,048,27921,909,030,0000.00  Hist 06/30/2023
Woodline Partners LP 1,035,5551,035,55521,643,100,0000.26  Hist 06/30/2023
FRED ALGER MANAGEMENT, LLC 1,010,0491,010,04921,110,024,0000.11  Hist 06/30/2023
RTW INVESTMENTS, LP 978,310978,31020,446,679,0000.39  Hist 06/30/2023
FRANKLIN RESOURCES INC 879,268879,26818,376,701,0000.01  Hist 06/30/2023
BlackRock Inc. 847,895847,89517,721,006,0000.00  Hist 06/30/2023
Avidity Partners Management LP 750,000750,00015,675,000,0000.55  Hist 06/30/2023
MILLENNIUM MANAGEMENT LLC 732,020732,02015,299,218,0000.01  Hist 06/30/2023
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) 650,000650,00013,585,000,0000.29  Hist 06/30/2023
MASSACHUSETTS FINANCIAL SERVICES CO /MA/ 641,068641,06813,398,321,0000.00  Hist 06/30/2023
EAGLE ASSET MANAGEMENT INC 520,050520,05010,869,045,0000.06  Hist 06/30/2023
BRAIDWELL LP 500,000500,00010,450,000,0000.34  Hist 06/30/2023
AMERIPRISE FINANCIAL INC 404,823404,8238,460,804,0000.00  Hist 06/30/2023
ADAGE CAPITAL PARTNERS GP, L.L.C. 370,000370,0007,733,000,0000.02  Hist 06/30/2023
Redmile Group, LLC 364,493364,4937,617,904,0000.29  Hist 06/30/2023
GEODE CAPITAL MANAGEMENT, LLC 347,768347,7687,268,351,0000.00  Hist 06/30/2023
BALYASNY ASSET MANAGEMENT L.P. 233,398233,3984,878,018,0000.01  Hist 06/30/2023
VICTORY CAPITAL MANAGEMENT INC 212,323212,3234,437,551,0000.00  Hist 06/30/2023
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