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LOOMIS SAYLES & CO L P
> HGSI
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 02/14/2012 | HUMAN GENOME SCIENCES INC | HGSI | 33,408,542 | 33,408,542 | 306,022,245 | 306,022,245 | $9.16 |
| 12/12/2011 | HUMAN GENOME SCIENCES INC | HGSI | 32,010,509 | 32,010,509 | 234,316,926 | 234,316,926 | $7.32 |
| 12/31/2010 | HUMAN GENOME SCIENCES INC | HGSI | 0 | -336,978 | 0 | -10,039,000 | |
| 09/30/2010 | HUMAN GENOME SCIENCES INC | HGSI | 336,978 | 12,839 | 10,039,000 | 2,694,000 | $29.79 |
| 06/30/2010 | HUMAN GENOME SCIENCES INC | HGSI | 324,139 | -4,202 | 7,345,000 | -2,571,000 | $22.66 |
| 03/31/2010 | HUMAN GENOME SCIENCES INC | HGSI | 328,341 | 268,762 | 9,916,000 | 8,093,000 | $30.20 |
| 12/31/2009 | HUMAN GENOME SCIENCES INC | HGSI | 59,579 | 59,279 | 1,823,000 | 1,820,000 | $30.60 |
| 03/31/2006 | HUMAN GENOME SCIENCES INC | HGSI | 300 | 0 | 3,000 | 0 | $10.00 |
| 12/31/2005 | HUMAN GENOME SCIENCES INC | HGSI | 300 | -215,200 | 3,000 | -2,926,000 | $10.00 |
| 09/30/2005 | HUMAN GENOME SCIENCES INC | HGSI | 215,500 | 133,450 | 2,929,000 | 1,979,000 | $13.59 |
| 06/30/2005 | HUMAN GENOME SCIENCES INC | HGSI | 82,050 | 775 | 950,000 | 201,000 | $11.58 |
| 03/31/2005 | HUMAN GENOME SCIENCES INC | HGSI | 81,275 | 71,500 | 749,000 | 632,000 | $9.22 |
| 12/31/2004 | HUMAN GENOME SCIENCES INC | HGSI | 9,775 | 9,475 | 117,000 | 114,000 | $11.97 |
| 07/01/2004 | HUMAN GENOME SCIENCES INC | HGSI | 300 | 0 | 3,000 | 0 | $10.00 |
| 06/30/2004 | HUMAN GENOME SCIENCES INC | HGSI | 300 | 0 | 3,000 | -1,000 | $10.00 |
| 03/31/2004 | HUMAN GENOME SCIENCES INC | HGSI | 300 | 0 | 4,000 | 0 | $13.33 |
| 12/31/2003 | HUMAN GENOME SCIENCES INC | HGSI | 300 | -111,000 | 4,000 | -1,516,000 | $13.33 |
| 09/30/2003 | HUMAN GENOME SCIENCES INC | HGSI | 111,300 | 111,000 | 1,520,000 | 1,516,000 | $13.66 |
| 06/30/2003 | HUMAN GENOME SCIENCES INC | HGSI | 300 | -200 | 4,000 | -2,000 | $13.33 |
| 09/30/2002 | HUMAN GENOME SCIENCES INC | HGSI | 500 | 0 | 6,000 | -1,000 | $12.00 |
| 06/30/2002 | HUMAN GENOME SCIENCES INC | HGSI | 500 | 0 | 7,000 | -4,000 | $14.00 |
| 03/31/2002 | HUMAN GENOME SCIENCES INC | HGSI | 500 | -500 | 11,000 | -23,000 | $22.00 |
| 12/31/2001 | HUMAN GENOME SCIENCES INC | HGSI | 1,000 | -94,950 | 34,000 | -2,932,000 | $34.00 |
| 09/30/2001 | HUMAN GENOME SCIENCES INC | HGSI | 95,950 | 2,850 | 2,966,000 | -2,643,000 | $30.91 |
| 06/30/2001 | HUMAN GENOME SCIENCES INC | HGSI | 93,100 | 500 | 5,609,000 | 1,349,000 | $60.25 |
| 03/31/2001 | HUMAN GENOME SCIENCES INC | HGSI | 92,600 | 61,600 | 4,260,000 | 2,111,000 | $46.00 |
| 12/31/2000 | HUMAN GENOME SCIENCES INC | HGSI | 31,000 | 15,400 | 2,149,000 | -552,000 | $69.32 |
| 09/30/2000 | HUMAN GENOME SCIENCES INC | HGSI | 15,600 | 15,600 | 2,701,000 | 2,701,000 | $173.14 |
| 03/31/2000 | HUMAN GENOME SCIENCES INC | HGSI | 0 | -2,000 | 0 | -305,000 | |
| 12/31/1999 | HUMAN GENOME SCIENCES INC | HGSI | 2,000 | 100 | 305,000 | 165,000 | $152.50 |
| 09/30/1999 | HUMAN GENOME SCIENCES INC | HGSI | 1,900 | 1,900 | 140,000 | 140,000 | $73.68 |
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