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ProShare Advisors LLC
> LXRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | LEXICON PHARMACEUTICALS, INC. | LXRX | 24,315 | -310 | 55,681,000 | 55,622,000 | $2,289.99 |
| 09/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 24,625 | 4,793 | 59,000 | 22,000 | $2.40 |
| 06/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 19,832 | -8,703 | 37,000 | -23,000 | $1.87 |
| 03/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 28,535 | -7,722 | 60,000 | -83,000 | $2.10 |
| 12/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 36,257 | 36,257 | 143,000 | 143,000 | $3.94 |
| 09/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 0 | -17,612 | 0 | -81,000 | |
| 06/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 17,612 | 17,612 | 81,000 | 81,000 | $4.60 |
| 12/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 0 | -22,321 | 0 | -32,000 | |
| 09/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 22,321 | -381 | 32,000 | -13,000 | $1.43 |
| 06/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 22,702 | 5,629 | 45,000 | 12,000 | $1.98 |
| 03/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 17,073 | -11,534 | 33,000 | -86,000 | $1.93 |
| 12/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 28,607 | -4,889 | 119,000 | 18,000 | $4.16 |
| 09/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 33,496 | -2,102 | 101,000 | -123,000 | $3.02 |
| 06/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 35,598 | -5,085 | 224,000 | -2,000 | $6.29 |
| 03/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 40,683 | 241 | 226,000 | -43,000 | $5.56 |
| 12/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 40,442 | -8,022 | 269,000 | -248,000 | $6.65 |
| 09/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 48,464 | -1,703 | 517,000 | -85,000 | $10.67 |
| 06/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 50,167 | -4,160 | 602,000 | 136,000 | $12.00 |
| 03/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 54,327 | -8,954 | 466,000 | -159,000 | $8.58 |
| 12/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 63,281 | 851 | 625,000 | -142,000 | $9.88 |
| 09/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 62,430 | 4,604 | 767,000 | -184,000 | $12.29 |
| 06/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 57,826 | -2,574 | 951,000 | 950,134 | $16.45 |
| 03/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 60,400 | -15,119 | 866 | -1,043,134 | $0.01 |
| 12/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 75,519 | 4,517 | 1,044,000 | -239,000 | $13.82 |
| 09/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 71,002 | -11,451 | 1,283,000 | 100,000 | $18.07 |
| 06/30/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 82,453 | 663 | 1,183,000 | 206,000 | $14.35 |
| 03/31/2016 | LEXICON PHARMACEUTICALS, INC. | LXRX | 81,790 | 81,790 | 977,000 | 977,000 | $11.95 |
| 12/31/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 89,382 | 89,382 | 1,190,000 | 1,190,000 | $13.31 |
| 09/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 0 | -88,031 | 0 | -709,000 | |
| 06/30/2015 | LEXICON PHARMACEUTICALS, INC. | LXRX | 88,031 | 88,031 | 709,000 | 709,000 | $8.05 |
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