METABASIS THERAPEUTICS INC (MBRX) [Rocket]

Ownership

METABASIS THERAPEUTICS INC (MBRX)

Portfolio as of:

Name	Shares	Change	Value	% Port	% OS	Hist	Date
LIGAND PHARMACEUTICALS INC	35,147,294	35,147,294	10,895,661			Hist	01/27/2010
FEDERATED HERMES, INC.	1,687,149	-187,311	1,906,000	0.01		Hist	09/30/2008
MPM ASSET MANAGEMENT LLC	4,814,725	0	1,878,000	1.45		Hist	12/31/2009
WELLINGTON MANAGEMENT GROUP LLP	3,803,464	-171,800	1,669,000	0.00		Hist	09/30/2009
CREDIT SUISSE AG/	3,863,422	0	1,487,000	0.00		Hist	12/31/2009
INTERWEST PARTNERS VII L P	4,279,029	4,279,029	1,369,289			Hist	12/31/2008
BAKER BROS. ADVISORS LP	1,985,603	-33,300	764,000	0.05		Hist	12/31/2009
Efficient Market Advisors, LLC	717,820	717,820	301,000	0.32		Hist	12/31/2009
DELTEC ASSET MANAGEMENT LLC	633,541	633,541	244,000	0.08		Hist	12/31/2009
WILLIAM HARRIS INVESTORS INC	620,346	0	239,000	0.09		Hist	12/31/2009
MILLENNIUM MANAGEMENT LLC	560,800	560,800	216,000	0.00		Hist	12/31/2009
DIMENSIONAL FUND ADVISORS LP	508,114	-3,500	196,000	0.00		Hist	12/31/2009
RENAISSANCE TECHNOLOGIES LLC	502,700	200,800	194,000	0.00		Hist	12/31/2009
WELLCOME TRUST LTD (THE) as trustee of the WELLCOME TRUST	474,833	0	183,000	0.01		Hist	12/31/2009
VANGUARD GROUP INC	395,811	47,700	152,000	0.00		Hist	12/31/2009
QVT Financial LP	389,319	0	150,000	0.00		Hist	12/31/2009
DIKER MANAGEMENT LLC	81,647	81,647	92,000	0.03		Hist	09/30/2008
BlackRock Institutional Trust Company, N.A.	220,166	-401,601	85,000	0.00		Hist	12/31/2009
BAKER FELIX	111,674	-2,250,318	43,553			Hist	12/31/2009
AMERIPRISE FINANCIAL INC	6,547	6,547	7,000	0.00		Hist	09/30/2008
Bascom Hill Partners, LLC	15,000	15,000	6,000	0.00		Hist	12/31/2009
KNIGHT CAPITAL GROUP LLC	13,474	13,474	5,000	0.00		Hist	12/31/2009
UBS AG	10,093	9,593	4,000	0.00		Hist	12/31/2009
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO	27,729	27,729	209	0.00		Hist	06/30/2010
RBC Capital Markets, LLC	100	100	113	0.00		Hist	09/30/2008